04 Dec 2025

Artera Secures $65M Growth Investment After Reaching $100M ARR

Artera has announced a $65 million growth investment led by Lead Edge Capital, joined by existing investors Jackson Square Ventures, Health Velocity Capital, and Heritage Medical Systems. The financing follows the company’s achievement of $100 million in contracted annual recurring revenue by the end of 2025, marking a significant validation of its long-term focus on AI-driven patient communication infrastructure. The organization’s decade of deep EHR integration and large-scale interaction datasets has continued to position it competitively as demand for Agentic AI tools accelerates across healthcare.

Healthcare providers have been facing substantial administrative and communication burdens, driven by fragmented systems, outdated on-premise technology, and an expanding landscape of niche vendors. Artera has framed its platform as an operational layer for patient access, supporting communication, scheduling, intake, and payments across text, email, and AI-driven agents. Its decade-long investment in applied AI underpins its agentic capabilities, which are designed to resolve patient access needs at scale.

According to CEO and Co-Founder Guillaume de Zwirek, the race to implement Agentic AI “will not be won with technology alone”. He emphasized that meaningful deployment requires three enduring advantages: the knowledge base of over two billion patient-provider interactions, a distribution network of more than 1,000 providers with deep integrations into systems such as Oracle Health and MEDITECH, and established infrastructure standards including support for Model Context Protocol and the Harmony platform.

Artera’s suite of AI Agents, Flows Agents, and Co-Pilots has already been adopted across hundreds of organizations. Its Flows Agents manage more than 42 million unique sessions annually and complete 94% of interactions without staff involvement. These capabilities provide a clear pathway toward fully autonomous agentic workflows supporting scheduling, rescheduling, triage, prescription refills, and post-discharge engagement. De Zwirek noted, “It’s not just about Agents automating a phone call; it’s about Agents and humans transforming the entire patient journey together.”

The company also highlights its security and compliance posture, with SOC 2 Type 2, HITRUST Certification, and HIPAA compliance, and stresses that PHI and PII are not used to train models. Its footprint spans federal agencies—including the Department of Veterans Affairs, Department of Defense, and Indian Health Service—and it provides white-labeled communications for major EHR platforms. More than 50 digital health vendors use Artera’s APIs for unified communication. The new funding will advance Artera’s next phase of agentic automation and sustain its position in patient access technology.

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