A new generation of AI-enabled digital health tools is emerging, offering continuous, personalized insights that help patients connect the dots and take control of their health. Powered by agentic AI and the latest LLMs, these solutions have the potential to empower patients, reduce the burden on clinicians, close critical care gaps, and deliver more personal, precise recommendations to manage their health. Drawing on these innovations, we’ll explore how AI-enhanced tools can drive engagement in preventative health and provide new learnings to fuel research. We’ll also discuss key considerations around privacy, security, and accessibility, and what’s needed to deliver personalized health insights responsibly and equitably. Together, these advances are creating the evidence base needed to power precision health.