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01 Aug 2025

ARCHIMED Acquires Arkstone to Scale AI-Powered Fight Against Antimicrobial Resistance

Healthcare-focused private equity firm ARCHIMED has acquired Arkstone, a pioneer in machine learning and artificial intelligence solutions for infectious disease management and antimicrobial stewardship. While financial terms remain undisclosed, the acquisition positions Arkstone to significantly expand its global reach in combating antimicrobial resistance, one of the most pressing public health challenges worldwide.

Arkstone's flagship product, the OneChoice Report, employs human-in-the-loop machine learning and artificial intelligence to generate optimal treatment recommendations for infectious diseases. The platform analyzes laboratory results in conjunction with patient data, delivering patient-specific guidance to clinicians at the precise moment lab results become available. This technology is already deployed in laboratories across the United States and internationally, fundamentally changing how healthcare providers approach infectious disease diagnosis and treatment.

The acquisition comes at a crucial time in the global fight against antimicrobial resistance. By providing precision-guided recommendations at the point of care, Arkstone's technology helps reduce inappropriate antibiotic use while ensuring patients receive the most effective treatments for their specific infections. This targeted approach is essential for preserving the effectiveness of existing antibiotics and slowing the development of resistant pathogens.

"Arkstone's OneChoice Report is redefining infectious disease management. Our partnership will enable Arkstone to reach more markets, accelerate product innovation, and ultimately save lives by reducing the misuse of antibiotics," stated Igor Petricca, Partner at ARCHIMED. "This deal offers an additional dimension, as Clinical Decision Support software (CDS) and infectious disease are at the crossroads of hot subsectors of our Healthcare IT and Diagnostics franchises."

ARCHIMED's investment brings more than capital to the partnership. The firm's extensive healthcare expertise and established international network will accelerate Arkstone's expansion into new geographic markets. This global reach is particularly significant given the worldwide nature of antimicrobial resistance, which requires coordinated international efforts to address effectively.

Post-acquisition, Arkstone will maintain operational continuity with its existing team remaining in place. This stability ensures that the company's deep expertise in infectious disease management and clinical decision support will continue to drive innovation. The focus moving forward will be on rapid growth, enhanced product development, and strategic market entry initiatives.

The partnership represents a strategic alignment between ARCHIMED's investment focus and Arkstone's mission. By positioning clinical decision support software at the intersection of healthcare IT and diagnostics, the acquisition recognizes the growing importance of AI-driven tools in modern healthcare delivery. These technologies are increasingly essential for managing complex clinical decisions, particularly in areas like infectious disease where rapid, accurate treatment decisions can significantly impact patient outcomes.

Arkstone's next phase will leverage ARCHIMED's resources to scale its impact on antimicrobial stewardship globally. The company plans to enhance its R&D capabilities, expand its product portfolio, and bring its precision-guided technology to more clinicians worldwide. This expansion is critical as healthcare systems globally seek effective tools to combat antimicrobial resistance while maintaining high standards of patient care.

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