GoodRx, WeightWatchers, and LifeMD have launched the newly FDA-approved Wegovy pill (oral semaglutide) with a transparent $149 per month cash-pay price, signaling a major shift in obesity care. Approved by the FDA on December 22, 2025, Wegovy is the first oral GLP-1 therapy indicated for chronic weight management and cardiovascular risk reduction. Clinical data from a 64-week Phase 3 trial showed a 16.6% mean weight loss, delivering efficacy comparable to injectable GLP-1s while eliminating injection-related barriers to adoption.
The oral formulation is aimed at people reluctant to start weekly injections, offering a more convenient, consumer-friendly option that may improve adherence. To accelerate access, GoodRx and LifeMD are bypassing traditional payer models and launching with a cash-pay strategy. Initial pricing sets the 1.5mg and 4mg doses at $149 per month, with changes planned after April 15, 2026: the 4mg dose rising to $199 and higher maintenance doses (9mg and 25mg) priced at $299 per month. GoodRx is listing the medication across a nationwide network of 70,000 pharmacies, while LifeMD supports access through its telehealth infrastructure.
The rollout represents one of the most aggressive efforts yet to scale medical weight management. By pairing Novo Nordisk’s clinical benchmark with broad digital and retail distribution, the partners are reframing GLP-1 treatment as a streamlined, transparent consumer experience rather than a complex medical process dominated by injections and opaque pricing.