Science and policy don’t always see eye-to-eye. We witnessed this push and pull throughout the pandemic, now the attention has turned towards the global vaccine rollout. With the US and other developed nations charging well ahead of the average global rate, it poses a crucial ethical dilemma that goes beyond the science of vaccinations. Where did we make the “right” decisions both domestically and internationally and how can we expand access and education to combat ongoing vaccine hesitancy, systemic barriers and new variants?