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19 - 22 Oct 2025 | Las Vegas

How Not to Accept the Status Quo: A Conversation with Mark Cuban

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Speakers:

Mark Cuban Entrepreneur, Co-FounderCost Plus Drugs
Mark Cuban
Entrepreneur, Co-FounderCost Plus Drugs
Zach Stafford HostSiriusXM
Zach Stafford
HostSiriusXM

About this Session:

Mark Cuban has never been one to accept broken systems quietly. His latest venture in healthcare is reshaping how Americans access and pay for medications. His approach isn’t about flashy tech demos or AI buzzwords; it’s about eliminating the middlemen, markups, and bureaucracy that drive up costs while delivering little value to patients. Through Cost Plus Drugs, he’s proven that radical price transparency and direct-to-consumer models can slash prescription costs by cutting out PBMs and other intermediaries that profit from the current complexity in our system. As both investor and entrepreneur, he brings a unique perspective on which digital health solutions actually solve real problems. His market-based approach to healthcare reform often puts him at odds with both traditional industry players and policy advocates, arguing that competition and transparency can drive down costs more effectively than regulation. This conversation promises to be characteristically blunt, covering price transparency to entrepreneurship to policy, and Mark’s core belief that healthcare should be accessible to all Americans.