Did you know that AI can predict clinical trial failure before a single patient is enrolled? Well with drug development costs skyrocketing and more than a 90% clinical trial failure rate, turning to AI to simulate entire studies upfront seems like a smart move. By modeling outcomes in advance, AI can flag likely failures, streamline trial design, save time, money and patients from unnecessary exposure. But this promise is far from the current reality. Many AI models struggle with limited or biased data, lack transparency in their decision-making, and often don’t generalize beyond the datasets used for training. There are also regulatory and ethical hurdles. Until those data, validation, and oversight challenges are resolved, AI’s dominance in clinical trials is yet to be seen.